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Polynucleotide Treatment at Shumaila’s London
Give your skin a natural boost with Polynucleotide Treatment, a new and powerful way to refresh and repair it. This treatment uses biocompatible DNA fragments that help your skin heal, boost hydration, and stimulate collagen production—leaving it smoother, firmer, and more youthful.
Now available at all Shumaila’s London clinics.
What Are Polynucleotides?
Polynucleotides are tiny, natural pieces of DNA, usually taken from fish like salmon or trout. These powerful molecules activate your skin’s natural repair system from within.
They work by:
- Fixing damaged skin tissue
- Activating your skin’s natural healing cells (called fibroblasts)
- Helping your skin look fresh, smooth, and healthy again
Polynucleotides don’t just fill or plump the skin like dermal fillers (facial fillers). Instead, they wake up your skin’s natural power to repair, renew, and glow. That’s why they’re an excellent option for anyone with:
- Ageing or tired-looking skin
- Dull or uneven skin tone
- Sensitive or inflamed skin
How Do Polynucleotides Work?
Polynucleotide treatment is an injectable procedure in which tiny shots are given just under the skin. They help your skin heal and look better from the inside out.
Once injected, polynucleotides:
Wake up your skin’s repair cells (called fibroblasts) to make more collagen and elastin.
- Add moisture to keep your skin soft and elastic.
- Reduce uneven skin tone and calm redness or irritation.
- Help your skin grow stronger and healthier over time.
At Shumaila’s London, we use safe, medical-grade polynucleotide products like Plinest (a Bio-filler/Non-toxic solution) and Nucleadyn (a bio-stimulator injectable substance) for the best results.
Plinest and Nucleadyn are advanced, clinically tested formulas for long-term skin regeneration.
Key Benefits of Polynucleotides Treatment
- Adds moisture to dry or thin skin
- Smooths out fine lines, wrinkles, and acne marks
- Makes skin firmer and more elastic
- Protects your skin – great for sensitive skin or rosacea (redness on the face)
- Lightens dark circles and makes tired eyes look fresh
- Helps your skin make more collagen over time for lasting results
Areas We Treat
Polynucleotide injections can be used on many parts of the body to help your skin heal and look fresher, including:
Under the eyes
for dark circles and fine under-eye wrinkles.
Cheeks and whole face
to smooth and refresh your look.
Neck and chest
to firm and brighten these delicate areas.
Hands
to make them look younger and less dry.
Acne-scarred skin
to improve texture and help it heal.
Polynucleotides for Skin
Polynucleotides are tiny building blocks that help your skin repair and stay healthy. They boost collagen, make skin smoother, and reduce signs of ageing. These special molecules also help heal and give your skin a fresh, glowing look. It’s like giving your skin a natural energy drink!
Polynucleotides for Eye-Repair
Polynucleotide injections target the delicate under-eye area to reduce dark circles, puffiness, and fine lines. By stimulating collagen and hydration, they restore a refreshed, youthful appearance.
Procedure of Polynucleotides Treatment
Certainly! Here’s the procedure in bullet points:
- Begins with a consultation to assess your skin needs.
- Skin is cleansed and numbed for comfort.
- Polynucleotides are injected using fine needles just under the skin.
- Treatment takes around 20–30 minutes.
- No cuts or stitches – completely non-surgical.
- Minimal discomfort and no downtime.
- A course of 2–3 sessions is usually recommended for optimal results.
Excellent 4.9 out of 5
Showing our 4 & 5 star reviews
Rabia was very efficient and thorough…
Rabia was very efficient and thorough with my skincare advice. Talked me through every step and kept me upto date with what products to use going forward. Would highly recommend x
Customer, 3 days ago
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Ishrat was extremely professional and…
Ishrat was extremely professional and knowledgeable. She explained each procedure and was very thorough with the treatment
Amna, 6 days ago
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Affordable, well trained staff, fast results
The staff are very friendly and listened very well to all my concerns and were reassuring. I had 3 sessions of chemical peels and was also given products to use at home to maintain results. In terms of pricing, the treatments are very affordable compared to others. I would 100% recommend Shumaila’s as they have multiple treatments available
Mina M, 9 days ago
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Lavanya Raja, 9 days ago
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Thelma did a great job
Thelma did a great job. Alot of explaining and understanding. Good session thanks Thelma.
Sahar, 14 days ago
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Consumer, 27 days ago
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Great customer service with a lot of…
Great customer service with a lot of attention and care. Thanks Harpreet
António Barros, 27 days ago
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I’ve had such a good experience at…
I’ve had such a good experience at Shumaila’s. Simran is amazing and really attentive, she has given me the results I’ve been looking for. I would really recommend booking!
Catherine, 27 days ago
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Khadija, 28 days ago
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Michela Williams, 33 days ago
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Had the most thorough wax with Mandeep…
Had the most thorough wax with Mandeep who was incredibly attentive and helpful!
TK, 35 days ago
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Aasia did a fantastic job with my wax
Aasia did a fantastic job with my wax — she was incredibly thorough and made the whole experience as comfortable as possible. I really appreciated her attention to detail. Will definitely be back!
Clarisse Nicole S. Rizo, 35 days ago
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Very convenient
It was really easy to make an appointment and the opening times mean it's easy to fit an appointment around a busy schedule. My therapist was really helpful and accommodating to my requests.
Kathryn Ball, 38 days ago
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Fast and very professional service
Fast and very professional service. Prices adequate to the treatments performed. I recommend it to everyone.
Mario, 40 days ago
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Great service
Great experience from start to finish. Professional, friendly service and really happy with the results. Would definitely recommend.
Fergal Keaney, 44 days ago
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Humairah Ahmed, 45 days ago
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i am very happy from the service highly…
i am very happy from the service highly recommended special thanks to haleema di she is very nice
Navjot Kaur, 45 days ago
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What to Expect
- Treatment Time: Approx. 30–45 minutes
- Downtime: Minimal—mild redness or swelling may occur
- Results: Begin appearing in 2–4 weeks, improving progressively
- Course: Typically 2–3 sessions, spaced 2–4 weeks apart
Who Is This Treatment For?
Polynucleotide Treatment is excellent for people who want healthier, younger-looking skin without going too deep. It’s perfect for:
- Anyone 25 and older who wants to slow down the signs of ageing.
- People with dull, sensitive, or irritated skin.
- Those not ready for fillers but still want their skin to look better.
- Anyone healing from acne or skin damage.
Aftercare Advice
- Avoid applying makeup or active skincare for 24 hours.
- No heat treatments (saunas, sunbeds) or vigorous exercise for 48 hours.
- Use gentle, hydrating skincare products.
- Drink plenty of water to support skin renewal.
Showing our favorite reviews on 
Bernard Rebeiro
YesterdayMet nazia and upneet fantastic experience very pleased with the results definitely coming back for my future treatments.
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Upminster
4.8
Business Grit
2 days agoGreat and efficient service, very happy with the result.
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Hammersmith
4.9
Musrufa Begum
5 days agoI had a deep cleanse with Huma who was very friendly and informative. Will be booking with her again.
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Seven Kings
4.8
Ek 1
5 days agoTreatment went well and Syeda did a great job with making sure it went smooth.
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Hammersmith
4.9
Sahara Dhir
6 days agoHad an amazing experience today at Sharmila‘s in Upminster. Nazia explained everything very professionally and the treatment was quick and painless as she promised. Would definitely recommend her.
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Upminster
4.8
Eisha Attaria
6 days agoGreat service by Rubeea
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Gants Hill
4.8
bhavesh Parmar
6 days agoIt's good response from store and I get proper treatment
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Upminster
4.8
Faylee
6 days agoHuma was fantastic with the Hollywood wax.
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Seven Kings
4.8
Megha Rathod
8 days agoI had my cosmelan treatment with dr kinda I felt good and comfortable with her Thanks dr kinza
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East Ham
4.7
Ali Najjar
9 days ago5* service all the way. Would highly recommend.
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Loughton
4.9
Vinal Pillai
14 days agoI went in for a free consultation with Nazia, who was absolutely amazing. She was friendly, knowledgeable, easy to talk to, and made the whole experience feel very comfortable. A fantastic consultation overall. I really appreciated her honest advice and professionalism. The only downside was the price I was quoted around £500 more than what several reputable clinics in central London are charging for the same treatment. As a result, I’ve decided to explore a well-reviewed clinic in Soho offering significantly more competitive pricing.
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Upminster
4.8
Tolulope Janet
14 days agoI really love this place. The staff and the manager are so lovely and respectful. They are so nice and lovely. I definitely have a lot to do at the shumaila’s and I would keep coming. I recommend 100%❤️❤️
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Upminster
4.8
terry yeomans
14 days agovery quick service lovely doctor. nazia. very very hapoy
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Upminster
4.8
Becky Brownlie
15 days agoI recently started going here and having my waxing done with Sonia & I am very happy with the results each time. The clinic is so clean, very professional & I’m in and out in great time too, they always run on time. Sonia is lovely and I always make sure to book her for my next one! Thank you!
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Upminster
4.8
Holly Ellyatt
17 days agoI regularly go to Shumaila’s and have treatments with Aasia and highly recommend her, she’s always very friendly, calm and kind and does a very professional job. Thanks Aasia and the team!
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East Ham
4.7
Laila Hussain
17 days agoMnal was very friendly helpful and lovely.
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East Ham
4.7
Maryam Rajpoot
19 days agoI got prominent results as they mentioned. Staff are very friendly.They briefly explian about the treatments . Specially meena is really nice and polite.
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Gants Hill
4.8
Gowri krishna
19 days agoHad a very good experience with Rabiya who was very kind and gentle with her approach.I would recommend clinic for every one.
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Gants Hill
4.8
Ami Naidu
19 days agoDr kinza is amazing very polite and kind she knows what she is doing. She is the best
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East Ham
4.7
Nikki Raf
20 days agoMnal is a fantastic therapist kind caring and thorough highly recommend her.
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East Ham
4.7
Prices And Offers On Polynucleotide Treatment
| Polynucleotide Eye Repair | Price |
| Polynucleotide Eye Repair (ameela) | £350 |
| Polynucleotide Eye Repair (nucleofil) | £250 |
| Polynucleotide Eye Repair (pdrn) | £220 |
| Polynucleotide Eye Repair (plinest) | £250 |
| Polynucleotide Eye Repair (vitaran I) | £220 |
| Polynucleotide Skin Repair | Price |
| Polynucleotide Skin Repair (ameela) | £350 |
| Polynucleotide Skin Repair (nucleofil) | £250 |
| Polynucleotide Skin Repair (pdrn) | £220 |
| Polynucleotide Skin Repair (plinest) | £250 |
| Polynucleotide Skin Repair (vitaran Ii) | £250 |
Frequent Asked Questions
You may feel mild discomfort, but numbing cream is applied beforehand to ensure comfort.
Most clients benefit from 2–3 sessions spaced 2–4 weeks apart, followed by maintenance every 6–9 months
Yes! Polynucleotides pair beautifully with microneedling, Profhilo, and chemical peels.
Absolutely. Polynucleotide injections are gentle and ideal for even the most sensitive or reactive skin types.
It depends on the area you want to treat and the number of sessions needed. A personalised consultation can give you an exact quote.
Choose Shumaila’s
Watch our video
Why Choose Shumaila’s London?
With over 9 locations across the UK and one in Pakistan, Shumaila’s London is a trusted leader in non-surgical aesthetic treatments.
Our trained experts use the latest skin science and premium injectables to deliver natural-looking results with clinical precision.
Expect personalised care, visible results, and long-term skin transformation.
Book Your FREE Polynucleotide Consultation Today!
Start your journey to firmer, healthier skin today!
Book a personalised consultation at your nearest Shumaila’s London clinic and discover how Polynucleotide Treatment can transform your skin from within.